Thursday, July 3, 2008

Evaluation of the commonest site, demographic profile and most effective therapy in scabies

Sudip Das, Tapas Chatterjee, G Banerji and Indranil Biswas

Indian J Dermatol 2006:51(3):186-8


Abstract:
The study was planned to find out the commonest sites of scabies in Indian patients. Attempts was made to study the demographic profile i.e., the commonest age group, affection of family members, friends or sexual partners, type of skin lesions, history of previous affection of scabies, co-association with STDs, and to find out the most effective treatment of scabies. Our study showed that the genitalia and finger webs were the most common sites and papular lesions were by far the commonest lesions in scabies. Oral Ivermectin remained the most effective drug closely followed by topical 5% permethrin cream.

Summary:
1. Papular lesions were the commonest (76%), followed by eczematous lesions (24%) and papulovesicular (23%).

2. Burrows, the most characteristic lesion, was seen in 17% of cases.

3. Previous affection with scabies were seen in 25% of cases and association with STDs were noted in 3.5% (7/200) of cases.

4. Genitalia (60%) was the commonest site, followed by finger webs (57%), lower abdomen (48%), umbilicus (42%), inner thighs (38%), wrists (41%), and buttocks (40%). Other rare sites include palms and soles (9%), lower legs (2%), back (2%), scalp (1%) and face (1%).

5. Ivermectin (200 ug/kg of BW) given in 2 doses at 2 weeks interval showed the best results with 96% improvement clinically and 100% reduction in itching at 4 weeks.

6. Permethrin 5% cream (overnight single application) also showed good results with 90% improvement clinically as well as in itching at 4 weeks.

7. Gamma Benzene Hexachloride 1% (2 consecutive overnight applications) showed 65% improvement clinically and 70% reduction in itching at 4 weeks.

8. No adverse effect was documented in all the patients studied.

Source: IJD

Tuesday, July 1, 2008

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